Finding new ways to repurpose or combine existing drugs has proved to be a powerful tool to treat complex diseases. Drugs used to treat one type of cancer, for instance, have effectively strengthened treatments for other cancer cells. Complex malignant tumors often require a combination of drugs or “drug cocktails,” to formulate a concerted attack on multiple cell types. Drug cocktails can not only help stave off drug resistance but also minimize harmful side effects.
But finding an effective combination of existing drugs at the right dose is extremely challenging, partly because there are near-infinite possibilities.