Article: Bio-hackers sidestep Big Pharma with new open-source insulin

Cures, Drugs, Open Health

Bio-hackers sidestep Big Pharma with new open-source insulin

Estimates find that some 10 percent of all Americans have diabetes, but just three companies manufacture the life-saving medicine needed to treat it. That’s believed to explain why diabetes has become the most expensive chronic condition in the United States, with prices doubling between 2012 and 2016.

An organization called Open Insulin hopes to change the calculus by creating open-source alternatives to the insulin made by the Big Three. The non-profit group is producing not only the compositions for insulin, but also hardware equivalents to the production equipment used by major pharmaceutical companies. The idea is that any community around the world could use the instructions to spin up their own small-scale manufacturing and meet local needs.

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Article: Six Penn faculty members launch free, open-source course on COVID-19, mRNA vaccines

Open Health, Procedures (Medical)

Six Penn faculty members launch free, open-source course on COVID-19, mRNA vaccines

Penn Medicine has partnered with the virtual course provider edX to launch a free virtual course taught by six Penn faculty on COVID-19 and the science behind mRNA vaccines. The instructors said they created the course in the hopes that it will help people understand the science of vaccines and encourage people to get the COVID-19 vaccine.

The virtual course, titled “The COVID-19 Pandemic and the Use of mRNA Vaccines,” is headed by Professor of Medicine Drew Weissman, a pioneer researcher of mRNA vaccine technology. The asynchronous, self-guided course is hosted on the edX website, meaning students can enroll at any time, and edX estimates that it can be completed in two weeks.

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Article: Digital is driving open concepts in several industries

Money, Open Governance, Open Health, Procedures (Medical)

Digital is driving open concepts in several industries

The concept of open office has transformed much of the work life. This was driven primarily by the desire to improve collaboration, efficiency and effectiveness. In the context of a rapidly evolving digital platform, similar impetus for collaboration is shaping some of the underlying industries of the US economy.

Different industry sectors deal with the concept of openness in different ways, and the factors that drive the concept of “open industry” are different. However, there are clear similarities. Increased openness is seen as the key to digital success and customer satisfaction, and with the rapid acceleration of digital platforms, it is needed as well as smart.

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Article: The Future of Business Is Open: How Open Data Is Changing Established Industries

Access, Money, Open Decision-Support, Open Governance, Open Health, Procedures (Medical)

The Future of Business Is Open: How Open Data Is Changing Established Industries

The open office concept reshaped much of working life — and was largely driven by a desire to improve collaboration, efficiency and effectiveness. A similar drive for collaboration is reshaping some bedrock industries of the American economy, albeit in the context of quickly evolving digital platforms.

Different industry sectors have treated concepts of openness with a range of responses, and the factors pushing them toward the “open industry” concept also differ. But there are definite similarities, as increased openness is seen as a key to digital success and customer satisfaction, one that quickly accelerating digital platforms make not only smart but necessary.

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Article: CDISC Teams Up with Microsoft to Develop Open-Source Software for the Clinical Research Community

Drugs, Open Decision-Support, Open Health, Procedures (Medical), Research

CDISC Teams Up with Microsoft to Develop Open-Source Software for the Clinical Research Community

CDISC is teaming up with Microsoft to develop the CDISC Open Rules Engine (CORE), open-source software that executes machine-readable CDISC Conformance Rules. The global clinical research community will be able to leverage the CORE software to test study data for conformance to CDISC standards as well as regulatory and sponsor-specific conformance rule sets.

CDISC Conformance Rules as well as regulatory agency rules provide a critical quality check in ensuring study data conform to CDISC standards. An emerging industry best practice is to use Conformance Rules on an ongoing basis, throughout the study, to keep the data as close to submission ready as possible and to ensure quality in all data exchange scenarios.

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Article: Waste-water surveillance can track Covid at an early stage: Dr. Angela Chaudhuri, COVIDActionCollab.

Open Health, Open Provisioning, Procedures (Medical), Water

Waste-water surveillance can track Covid at an early stage: Dr. Angela Chaudhuri, COVIDActionCollab.

Precision Health is a platform that is open to initiatives and organizations who want to study environments like wastewater for Covid-19, antimicrobial resistance, and other viruses. The Precision Health Platform in Bengaluru will test sewage from both sewered and non-sewered wastewater to identify clusters of new infections.

Tell us about the latest advancements in the tracking of COVID-19 through Sewage Water?
If we look at the concept of Sewage testing specifically for diseases, the concept originated in the 1920’s in Ireland to test for Typhoid.

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Article: North Cumbria Integrated Care chooses Better solution for e-prescribing

Open Governance, Open Health, Procedures (Medical), Standards

North Cumbria Integrated Care chooses Better solution for e-prescribing

The platform will be operational across the trust’s acute and community hospitals and will be implemented in partnership with CGI. The Better Meds solution will support the immediate integration of the trust’s existing decision support systems as well as its pharmacy and Omnicell automated dispensing cabinets.

The solution is built on an openEHR platform to allow further integration with new systems in the future. It marks the next step in the trust’s ambition to move away from paper-based systems towards a central EPR model, intended to improve the delivery of hospital and community health services to more than half a million people.

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Article: ‘Loop’ artificial pancreas software safe, effective with community support

Drugs, Open Health, Procedures (Medical)

Loop’ artificial pancreas software safe, effective with community support

The Loop open-source system for a do-it-yourself automated insulin delivery system can be initiated with community-developed resources and used safely and effectively by adults and children with type 1 diabetes, real-world data show.

“This large prospective study of the popular Loop open-source DIY automated insulin delivery system showed that adults and children with type 1 diabetes can successfully initiate the system, use it safely, and improve their glucose control with it,”

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Article: Indian tech cos join hands to make open source based oxygen concentrators; to be priced at around Rs 40k

Design, Open Health, Open Space

Indian tech cos join hands to make open source based oxygen concentrators; to be priced at around Rs 40k

A group of small and medium Indian technology companies and a defence PSU have joined hands to manufacture oxygen concentrators based on an open source design project Marut, initiated by robotic and automation startup Technido to meet the immediate need of patients and reduce dependency on imports.

According to the companies involved in the project, the oxygen concentrator (OC) with 10 litres per minute flow with purity of above 93 percent and capability to operate round-the-clock can be retailed at about half the price of imported units in the range of Rs 65,000-70,000 per piece.

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Article: Use single-cell biology to shed light on pediatric diseases currently in the dark

Cures, Document, Open Decision-Support, Open Health, Research

Use single-cell biology to shed light on pediatric diseases currently in the dark

There are few things harder for a physician to say to a patient than “I don’t know what’s wrong.” Saying that is even harder when you’re sitting across from the parent of a child with an undiagnosed condition.

And as I learned from experience, it is harder still when you work at a national referral center for rare pediatric diseases, since you are a family’s last hope: the physician they’re seeing after they’ve spent months — even years — searching for help and exhausting every other option. My heart broke every time I had to say, “I’m so sorry, but I don’t know what’s wrong.”

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